Dr Alexander Lyon | Royal Brompton & Harefield Hospitals Education

Dr Alexander Lyon

Consultant cardiologist
Specialises in cardiomyopathy, cardio-oncology, heart failure and Takotsubo syndrome.

Dr Alexander Lyon, consultant cardiologist is the heart failure team lead and the cardiovascular biomedical research unit lead at Royal Brompton & Harefield Hospitals. 

Dr Alexander Lyon studied at the University of Oxford, then trained as a junior doctor in cardiology in Oxford, London and in Sydney, Australia. In 2005, he was awarded an MRC Clinical Research Training Fellowship and studied the influence of cardiac gene therapy on ventricular arrhythmia generation. In 2008 he completed his PhD and finished his cardiology training at St Mary’s Hospital and Royal Brompton Hospital. 

Dr Lyon has received several academic awards from the British Society for Cardiovascular Research, British Cardiovascular Society, Medical Research Society, International Society of Heart Research and the Royal Society of Medicine. 

Clinical expertise

Dr Alexander Lyon is an expert in hypertension, heart valve disease, coronary artery disease, cardiomyopathy and specialises in heart failure, cardiac gene therapy, Takotsubo syndrome, cardiovascular diseases caused by cancer treatments, known as cardio-oncology, chemotherapy-induced heart failure and novel molecular and biological therapies for heart failure.  He runs a specialist clinic focusing on risk prediction and management of refractory symptoms for patients with Takotsubo syndrome. 

Dr Lyon also specialises in the investigation of cardiac symptoms such as breathlessness, dizzy spells, chest pain, palpitations, and general cardiac health checks to guide risk factor management.   

Research interests

Dr Lyon’s extensive involvement in research in his field is pivotal to leading new strategies for treatments. He is the lead for the heart failure research team of the National Institute of Health Research (NIHR) cardiovascular biomedical research unit (cBRU) at Royal Brompton Hospital as well as a co-investigator at the BHF Centre for Cardiovascular Regenerative Medicine at Imperial College London. 


Dr Alexander Lyon has reviewed manuscripts for various scientific journals which include the British Journal of Pharmacology, Circulation Research, Journal of Cardiac Failure, Cardiology, British Medical Journal, European Journal of Heart Failure, American Journal of Physiology, Progress in Neuro-Psychopharmacology, Biological Psychiatry and Medical Science Monitor. 


Dr Alexander Lyon is a senior lecturer at Imperial College London, where he supervises PhD students.  He has presented at numerous national and international meetings on regenerative medicine therapy in heart failure, chemotherapy-induced cardiac dysfunction and heart failure, cardiac calcium pathophysiology and Takotsubo cardiomyopathy