Professor Nicholas Simmonds - RB&HH Education

Professor Nicholas Simmonds

Associate director and consultant physician of Adult Cystic Fibrosis Centre at Royal Brompton Hospital.
Specialises in an expert in the care and management of adults with cystic fibrosis (CF).

Professor Nicholas Simmonds is associate director and consultant physician of the Adult Cystic Fibrosis Centre at Royal Brompton, and professor of practice (respiratory medicine) at the National Heart and Lung Institute, Imperial College London.

Clinical expertise

Professor Nicholas Simmonds is an expert in the care and management of adults with cystic fibrosis (CF). He is also, a leading expert in the difficult diagnosis of possible CF cases, leading a state-of-the-art national diagnostic service, Difficult CF Diagnosis Clinic, encompassing techniques such as nasal potential difference measurement, sweat testing and extended gene analysis. He is also the vice coordinator of the European CF Society (ECFS) Diagnostic Network Working Group.

Research interests

Professor Nicholas Simmonds’ research interests include CF survival variability, particularly variable CFTR gene/protein function. He is also an expert in clinical trials and trial development and is an Executive Committee member of the ECFS Clinical Trial Network.


In addition, he is a chief/principal investigator on numerous global multicentre trials. He is also on the Registry Research Committee of the UK CF Registry, a role which promotes the use of registries.


Professor Nicholas Simmonds has published widely, including original research in peer review journals, review articles, editorials, and book chapters.

He is on the editorial board of the Journal CHEST and was section editor for the journal Current Opinion in Pulmonary Medicine. He also co-edited the ECFS Living Longer with CF textbook.


Professor Simmonds is well-renowned in his expertise. He has given state-of-the-art educational lectures at numerous symposia at national and international conferences and meetings.


In addition, Professor Simmonds regularly teaches on the internationally renowned course ‘Managing the Care of Children and Adults with CF’.