Coronary sinus reducer for the treatment of angina and coronary microvascular dysfunction

08 Aug 2024

This Grand Round, presented by Dr Ranil de Silva, focuses on ‘Coronary sinus reducer for the treatment of angina and coronary microvascular dysfunction’.

Dr Ranil de Silva Background

Dr Ranil de Silva is a consultant interventional cardiologist and leads the specialist angina service at Royal Brompton Hospital, where he treats private and NHS patients.

In 1995, he graduated with honours from King’s College London with a degree in medicine. Following that he completed his training in general medicine, general cardiology and interventional cardiology at Royal Brompton, Chelsea and Westminster, Hammersmith, and St Mary’s hospitals in London.

He conducted his PhD research at the Medical Research Council Cyclotron Unit, Hammersmith Hospital, London, and at the Research Institute for Brain and Blood Vessels in Akita, Japan.

In particular, his research areas include: refractory angina, coronary microvascular dysfunction, coronary plaque biomechanics, novel cardiac magnetic resonance imaging techniques for the study of adverse left ventricular remodelling.

Dr Ranil de Silva Consultant interventional cardiologist

• Curated For : Secondary care doctors & Students & Tertiary care doctors
• Subject : Cardiology 45 Minutes

08 Aug 2024

This Grand Round will explore precision medicine with a specific focus on respiratory disease.

Professor Anke-Hilse Maitland-Van der Zee Background

Prof. Dr. A.H. Maitland-Van der Zee (Anke-Hilse) was trained as a pharmacist (1999 Groningen University), clinical pharmacologist and epidemiologist. She obtained her PhD in 2003 at Utrecht University and worked as a postdoc at the Human Genetics Center of the University of Texas in Houston, Tx USA from 2003-2005. From 2005-2016 she worked at the Division of Pharmacoepidemiology and Clinical Pharmacology of Utrecht University first as an assistant Professor and since 2012 an associate Professor. In 2016 she was appointed as a full Professor of Precision Medicine in Respiratory Disease at the Academic Medical Center in Amsterdam.

Professor Anke-Hilse Maitland-Van der Zee

• Curated For : Nurse & Primary care doctors & Secondary care doctors & Students & Tertiary care doctors
• Subject : Respiratory medicine 1 Hour

11 Jul 2024

This talk presented by Dr Hatem Soliman Aboumarie focuses on lung ultrasound in acute care.

Dr Hatem Soliman Aboumarie Background

Dr Hatem Aboumarie is a consultant in cardiothoracic intensive care, clinical lead for organ donation and clinical lead for advanced critical care practitioners at Harefield Hospital. In addition to this role, he is an honorary senior lecturer at the School of Cardiovascular Medicine and Sciences at King’s College London.

Dr Hatem Aboumarie’s clinical expertise includes:

1. critical care management of various cardiac and respiratory disorders
2. management of patients on extracorporeal membrane oxygenation for respiratory failure and cardiogenic shock
3. management of different modalities of mechanical circulatory support including long-term left ventricular assist devices
4. management of heart and lung transplantation
5. expert application of echocardiography and point of care ultrasound in the intensive care unit.

Dr Hatem Soliman Aboumarie

• Curated For : Primary care doctors & Radiographers / technologists & Secondary care doctors & Students
• Subject : Respiratory medicine 30 Minutes

08 Jul 2024

This talks delivered by Dr Ee Ling Heng focuses on the transcatheter treatments options for valvular heart disease.

Learning Objectives

1. Scale of the problem
2. Aortic Stenosis and TAVI
3. Mitral Regurgitation and Edge-to-edge Repair
4. Tricuspid Regurgitation – the next frontier?

Dr Ee Ling Heng Background

Dr Ee Ling Heng, consultant cardiologist in adult congenital heart disease and structural intervention at the Royal Brompton and Harefield hospitals.

Dr Ee Ling Heng graduated from Imperial College London, with an intercalated BSc in Healthcare Management. She was awarded a British Heart Foundation Clinical Research Training Fellowship and completed her PhD investigating ‘Improved Outcome Prediction in Tetralogy of Fallot’.

Dr Ee Ling Heng has clinical expertise encompassing adult congenital heart disease and general cardiology. She has a special interest in structural and ACHD interventional procedures.

Dr Ee Ling Heng Adult congenital and structural interventional cardiologist

• Curated For : Primary care doctors & Secondary care doctors & Students & Tertiary care doctors
• Subject : Cardiology 40 Minutes

04 Jul 2024

This Grand Round focuses on the current state of atrial fibrillation in 2024 and the future challenges we might face to meet the needs and expectations of patients affected by atrial fibrillation.

Learning Objectives

1. Relevance of atrial fibrillation – a global picture
2. Digital applications for AF detection and treatment
3. Stroke prevention – oral anti-coagulation and beyond
4. AHRE – new trial data
5. Rational for rhythm control in AF
6. Catheter ablation – new technologies and new trial results
7. Future of AF therapies

Professor Gerhard Hindricks background

Prof. Gerhard Hindricks headed the Heart Center in Leipzig until February 2023 when he was appointed Head of Electrophysiology-Rhythmology at the German Heart Center of Charité, and Chief Integration Officer of the German Heart Center Berlin in March 2023. His main responsibilities in Berlin are the development of excellence in electro-physiology at Charité hospitals, the integration of the Charité hospitals to the German Heart Centre (as Chief Integration Officer) and to support the German Heart Centre of the Charité in fields of strategic development.

Professor Gerhard Hindricks

• Curated For : Nurse & Secondary care doctors & Students & Tertiary care doctors
• Subject : Cardiology 1 Hour

04 Jul 2024

This Grand Round explores a European collaborative study around childhood interstitial lung disease in survivors in adulthood.

Learning Objectives

1. Interstitial Lung Disease (ILD) in adult vs children
2. International Managment platform for ILD in children child U classification

Professor Effrosyni D. Manali

Effrosyni D. Manali is Associate Professor in Athens Medical School, National and Kapodistrian University of Athens, Greece. She had completed her fellowship in Athens, Greece; Paris, France and in Cleveland, USA. She works at the 2nd Pulmonary Medicine Department of General University Hospital “Attikon”. She is the author of more than 130 peer-review articles, 19 chapter-books and participates yearly in Graduate and Postgraduate courses in Pulmonary Medicine and Internal Medicine for students and fellows. She has special interest in rare diseases of the lungs and in interstitial lung
diseases; more specifically in the study of Greek adult and pediatric patients with inheritable pulmonary fibrosis. For that purpose, she is collaborating with expert centers of excellence in Europe. She co-chaired the European Respiratory Society Task Force on transition of pediatric patients with interstitial lung disease to the adult care.

Prof Effrosyni Manali

• Curated For : Clinical scientist & Nurse & Primary care doctors & Secondary care doctors & Students & Tertiary care doctors
• Subject : Paediatrics & Respiratory medicine 55 Minutes

01 Jul 2024

This talk focuses on endothelial studies focusing on patients with chronic lung disorders such as COPD or IPF.

Learning objectives

1. Role of endothelium in chronic lung disease
2. Endothelial studies using endothelial progenitors (ECFC)
3. Endothelial dysfunction in COPD – studies using ECFC

Dr Koralia Paschalaki Background

Koralia Paschalaki is a respiratory physician and Senior Clinical Research Fellow at the National Heart and Lung Institute. Her research is focused on the molecular mechanisms of endothelial dysfunction and vascular disease in patients with chronic lung disorders, including COPD and IPF. Using circulating endothelial progenitors, she has provided the first evidence of accelerated endothelial ageing (senescence) due to epigenetic dysfunction in patients with COPD, providing novel insights into the development of cardiovascular disease in this group. Her research work, employing primary endothelial cells and advanced organ-on-a-chip platforms, is currently funded by BHF, NIHR Biomedical Research Centre and pharma.

Koralia Paschalaki

• Curated For : Secondary care doctors & Tertiary care doctors
• Subject : Respiratory medicine 35 Minutes

23 May 2024

This Grand Round focuses on Antenatal onset adenocarcinoma treated on ECMO and it is delivered by Professor Andrew Bush, Professor Clair Hogg and Dr Michele Arigliani.

Professor Andrew Bush has research interests that include the invasive and non-invasive measurement of airway inflammation in children, in particular the use of endobronchial biopsy in the management of severe asthma, and clinical physiology, especially respiratory mass spectrometry.
Professor Claire Hogg is a leader in clinical research in PCD and novel diagnostics. Many new techniques, including 3-dimensional electron tomography and the validation of immunofluorescence for the diagnosis of PCD, have been developed in her research group and under her supervision. Her group is the first in the world to introduce the use of Artificial Intelligence to assist the diagnosis of PCD.
Dr Michele Arigliani is a paediatric respiratory fellow at RBH. His research interests are mostly focused on lung physiology and respiratory complications in children born preterm and in those with sickle cell disease. He has co-authored over 30 papers in peer-reviewed journals.

Professor Claire Hogg

• Curated For : Primary care doctors & Secondary care doctors & Students
• Subject : Respiratory medicine 30 Minutes

21 May 2024

This talk by Dr Wala Mattar, focuses on what GPs and primary care should be aware of and when they should consider referring patients to the heart failure services.

Learning objectives:

1. Definition of heart failure
2. Chronic vs acute heart failure
3. Heart failure with reduced ejection fraction vs preserved ventricular function
4. Cardiac rhythm management for heart failure with reduced ejection fraction
5. Multidisciplinary team management for the prevention and treatment of chronic heart failure

Dr Wala Mattar Background

Dr Wala Mattar is a consultant cardiologist, appointed at Watford General and Harefield Hospital in 2018.

Prior to this, Dr Mattar qualified from the Arabian Gulf University in the Kingdom of Bahrain in 2004, then specialised in internal medicine and cardiology. In 2011, she came to the UK to train in cardiology at Harefield Hospital. Her subspecialty interest is coronary and structural intervention and permanent pacemakers’ insertion.

Dr Wala Mattar Consultant general and interventional cardiologist

• Curated For : Primary care doctors & Secondary care doctors & Students
• Subject : Cardiology 40 Minutes

29 Apr 2024

The webinar focuses on cardiac MRI guideline indications  in patients with cardiovascular disease. It uses clinical cases to illustrate the role of cardiac MRI in identifying a final diagnosis, guide management and inform diagnosis. The spectrum of pathologies discussed spans from ischemic heart disease, chest pain, myocarditis, heart failure and various non-ischemic cardiomyopathic process, as well as hypertension.

Professor Chiara Bucciarelli-Ducci Background

Professor Bucciarelli-Ducci received her undergraduate degree (2001) and postgraduate fellowship in cardiology (2005) from the University of Rome “La Sapienza”, Italy.

She then undertook courses and fellowships at Northwestern University in Chicago, University of Zurich, Harvard Medical School, Oxford University and more recently an MSc in Health Economics from LSE. She worked at the Royal Brompton Hospital as a senior CMR clinical and research fellow in 2006-2010 and in 2012 she was awarded a PhD in CMR from the National Heart and Lung Institute, Imperial College.

She was appointed a consultant cardiologist at the Bristol Heart Institute and University of Bristol where she was headhunted in 2010 to build the CMR programme. In 2021 she then returned to Royal Brompton and Harefield Hospitals to lead the CMR clinical academic programme at Harefield.

Professor Chiara Bucciarelli-Ducci

• Curated For : Primary care doctors
• Subject : Cardiology 1 Hour 15 Minutes

25 Apr 2024

This Grand Round delivered by Professor Nicholas Simmonds covers Cystic Fibrosis diagnosis and CFTR function.

More specifically this Grand Round covers:

1. Pathopysiology
2. Diagnostic pathway and uncertainties
3. CFTR functional tests
4. Case examples
5. CFTR related disorders
6. Future directions

Professor Nicholas Simmonds Background

Professor Nicholas Simmonds is Associate Director of the Adult CF Centre at Brompton and Professor of Practice (Respiratory Medicine) at Imperial College London. His main research interests include difficult CF diagnosis and the investigation of novel CF therapies. He has been a Principal Investigator on numerous global multicentre trials and is on the Executive Committee of the European Cystic Fibrosis Society (ECFS) Clinical Trials Network. He has extensive experience of novel diagnostic techniques and is the Vice Coordinator of the ECFS Diagnostic Network. He is also on the Registry Research Committee of the UK CF Registry, a role which promotes the use of registries to better understand outcomes in CF.

Professor Nicholas Simmonds Associate director and consultant physician of Adult Cystic Fibrosis Centre at Royal Brompton Hospital.

• Curated For : Primary care doctors & Secondary care doctors & Students
• Subject : Respiratory medicine 45 Minutes

19 Apr 2024

This Grand Round presented by Dr Stanley Hazen focuses on the microbiome: how the gut speaks to the heart.

Dr Stanley Hazen Background

Dr. Stanley Hazen received his clinical training in Internal Medicine and sub specialty training in Diabetes, Endocrinology and Metabolism at Barnes/Jewish Hospital, and a PhD in Biophysical Chemistry and Molecular Biology from Washington University School of Medicine, St. Louis, MO. He holds multiple leadership positions at the Cleveland Clinic including chair, Department of Cardiovascular & Metabolic Sciences, co-section head, Preventive Cardiology & Rehabilitation, and Director, Center for Microbiome & Human Health.

Dr. Hazen is an elected fellow to both the National Academy of Medicine, USA, and the American Association for the Advancement of Science. He also is an elected member of the American Association
of Physicians

• Curated For : Allied Health Professional & Primary care doctors & Secondary care doctors & Students & Tertiary care doctors
• Subject : Cardiology 1 Hour